Research Center for Infectious Diseases and School of Biotechnology, International University, Vietnam National University, Ho Chi Minh City, Vietnam
Title of the talk: Pseudomonas aeruginosa: colonisation and antimicrobial resistance development
Abstract
Pseudomonas aeruginosa (P. aeruginosa) is a ubiquitous bacterium which can be found in most moisture places such as soil, water, food, plants, and animals including humans. This Gram-negative, rod-shaped, asporogenous, mono-flagellated microorganism has an extensively large and plastic genome which allows it to adapt effectively to surrounding environments. It is also a prevalent cause of nosocomial infections, contributing to high morbidity and mortality rates. In clinical settings, P. aeruginosa isolates have been documented to exhibit resistance to nearly all classes of commonly used antibiotics, including aminoglycosides, cephalosporins, fluoroquinolones, and carbapenems. In our research group, we investigated the presence of P. aeruginosa in humans and the environment as well as the biological characteristics of the isolates, their impact on diseases, and their plastic response to antibiotics. For this talk, a review of the current understanding of P. aeruginosa in the view of one health is provided. Furthermore, the contribution of our research group in this field is also present. There is no doubt that understanding this pathogen will help us get closer to effectively interfering with its pathogenesis and antibiotic resistance, which is an ever-challenging problem for public health.
Biography
A/Prof. Hoai Nguyen is a faculty and leader of Medical Microbiology Research Group of School of Biotechnology as well as Vice Director of the Research Center for Infectious Diseases, International University, Vietnam National University Ho Chi Minh City.
A/Prof Hoai Nguyen obtained a BSc degree from the Honor Program of Hanoi University of Natural Sciences, VNU-HN in 2003. In 2008, she received her Ph.D. degree from Greifswald University, Germany in Biomedical Sciences and did her postdoctoral research at Louvain Drug Research Institute, Université catholique de Louvain, Belgium, and National Institute of Allergy and Infectious Diseases, NIH, USA.
So far, she has published 3 book chapters and 75 papers with 25 ISI/Scopus papers. Dr Hoai Nguyen is working in the field of proteomics. She is interested in proteomic analysis of bacterial pathogens, development of rapid and accurate diagnostic tests for bacterial pathogens and their antimicrobial resistance genes as well as alternative therapies to antibiotics alone. She has served as a council member of Asia Oceania Agricultural Proteomics Organization as well as editor and reviewer of reputed scientific journals. She also contributes as a referee of Global Undergraduate Award, international fundings such as Thuthuka Funding Instrument/ South Africa Research Foundation and national fundings such as Nafosted, Vietnam National University and International University. She is serving as the ambassador of German Academic Exchange Service (DAAD) and American Society of Microbiology (ASM) in Vietnam. In 2023, she was awarded Vietnam National University’s Lecturer of the Year Award and L’Oreal-Unesco For Women In Science National Award.
Publications: Website ORCID ResearchGate